image showed above is rash in fibromyalgia major drug of choice in fibromyalgia is : snri = DULOXITINE MANAGEMENT Evidence-based guidelines by the American Pain Society (APS) for the optimal treatment of FMS. MEDICATIONS: Strong Evidence for Efficacy (Tricyclic Antidepressant Medications) Amitriptyline Cyclobenzaprine CNS agents, antidepressants, muscle relaxants, or anticonvulsants are the most successful pharmacotherapies. ref : kd tripathi 9th ed