Physiology In sickle cell disease: September 2007 A Glutamtic acid, at position No.5 of beta-globin chain of haemoglobin is replaced by valine B Glutamtic acid, at position No.6 of beta-globin chain of haemoglobin is replaced by valine C Valine at position No.6 of beta-globin chain of haemoglobin is replaced by glutamtic acid D Valine at position No.5 of beta-globin chain of haemoglobin is replaced by glutamtic acid π‘ Explanation In sickle cell disease: September 2007 β Correct Answer: B. Glutamtic acid, at position No.6 of beta-globin chain of haemoglobin is replaced by valine