Defects in Double-Strand Break Repairs: Defects in Single-Strand Break Repairs: Non-Homologous End Joining Repair (NHEJ) SCID (Severe Combined Immunodeficiency Disease) (RS-SCID) Radiation sensitive Severe Combined Immunodeficiency Disease Nucleotide excision Repair (NER) Xeroderma Pigmentosa Homologous Repair (HR) Bloom syndrome Werner syndrome Breast cancer Base Excision Repair (BER) MUTYH associated Polyposis Mismatch Repair (MMR) HNPCC (Hereditary Non-Polyposis Colorectal Cancer)