In RDS which is damaged?
Correct Answer: Type 1 pneumocytes
Description: In ARDS, alveolar capillary endothelial cells & type 1 pneumocytes(alveolar epithelial cells) are damaged/injured, leading to the loss of the normally tight alveolar barrier to fluid and macromolecules.
As a result, oedema fluid rich in protein accumulates in the interstitial & alveolar spaces. Condensed plasma proteins aggregate in the air spaces with cellular debris and dysfunctional pulmonary surfactant to form hyaline membrane whirls.
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