In minimal change disease, which of the following is seen?
**Core Concept**
Minimal change disease (MCD) is a type of nephrotic syndrome characterized by the loss of foot processes of podocytes, leading to massive proteinuria. The **glomeruli** appear normal under light microscopy but show **effacement of foot processes** under electron microscopy.
**Why the Correct Answer is Right**
Since the correct answer is not specified, let's focus on the characteristic feature of MCD, which is the loss of foot processes of **podocytes**. This leads to a disruption in the **glomerular filtration barrier**, resulting in massive proteinuria.
**Why Each Wrong Option is Incorrect**
**Option A:** Not provided, assuming it's a distractor.
**Option B:** Not provided, assuming it's a distractor.
**Option C:** Not provided, assuming it's a distractor.
**Option D:** Not provided, assuming it's a distractor.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that MCD is the most common cause of nephrotic syndrome in children and often responds well to **corticosteroid therapy**.
**Correct Answer:** Not provided, please fill in the correct answer choice and text.