Pathology In minimal change disease, albumin is first to appear in urine because: A Albumin has high affinity to glomerular basement membrane B Albumin has lower molecular weight compared to globulins C High albumin:globulin ratio in plasma D Active excretion of albumin 💡 Explanation In minimal change disease, albumin is first to appear in urine because: ✓ Correct Answer: B. Albumin has lower molecular weight compared to globulins