In lead poisoning, there is an inhibition of some of the enzymes of the heme biosynthetic pathway. This is reflected by the accumulation of what substance in blood?
Correct Answer: Delta amino levulinic acid
Description: Ans: D. Delta amino levulinic acid(Ref: Harper 30/e n329)Lead poisoning:Affect heme metabolism by combining with SH groups in ferrochelatase & ALA (delta-amino levulinic acid) dehydratase enzymes.Elevated protoporphyrin levels - Found in RBC's.Elevated ALA & coproporphyrin levels - Found in urine.
Category:
Biochemistry
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