In humans, telomeres have the following sequence
**Core Concept**
Telomeres are repetitive nucleotide sequences located at the ends of chromosomes, protecting them from deterioration and fusion with neighboring chromosomes. In humans, telomeres have a specific DNA sequence that is repeated multiple times.
**Why the Correct Answer is Right**
The correct sequence of human telomeres is TTAGGG, which is repeated multiple times. This sequence is rich in guanine, which helps to stabilize the telomere structure. The 3' overhang of the telomere is created by the enzyme telomerase, which adds nucleotides to the 3' end of the telomere. The TTAGGG sequence is crucial for the proper functioning of telomeres, as it allows them to bind to specific proteins that help to maintain chromosome stability.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not match the known sequence of human telomeres.
**Option B:** This option is incorrect because it is not a recognized sequence of human telomeres.
**Option C:** This option is incorrect because it does not match the known sequence of human telomeres.
**Clinical Pearl / High-Yield Fact**
Telomere shortening is a hallmark of aging, and it is also a feature of certain diseases, such as dyskeratosis congenita. Telomerase activation is a potential therapeutic strategy for diseases associated with telomere shortening.
**Correct Answer: C. TTAGGG**