In Herpes zoster keratitis all occurs except –
**Core Concept**
Herpes zoster keratitis is a viral infection of the cornea caused by the reactivation of varicella-zoster virus, leading to inflammation and damage to the corneal tissue. This condition often presents with symptoms such as eye pain, redness, and decreased vision.
**Why the Correct Answer is Right**
Herpes zoster keratitis can lead to various complications, including epithelial defects, stromal thinning, and endothelial decompensation. The condition is characterized by the formation of dendritic ulcers, which are branching, linear lesions on the corneal surface. The pathogenesis involves the reactivation of latent varicella-zoster virus in the trigeminal ganglion, followed by the migration of infected neurons to the cornea, where they release viral particles and trigger an inflammatory response.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because epithelial defects are a common manifestation of herpes zoster keratitis, as the virus can cause necrosis and ulceration of the corneal epithelium.
**Option B:** This option is incorrect because stromal thinning is a potential complication of herpes zoster keratitis, as the chronic inflammation and viral infection can lead to scarring and thinning of the corneal stroma.
**Option C:** This option is incorrect because endothelial decompensation is a possible outcome of herpes zoster keratitis, as the condition can cause damage to the corneal endothelium and lead to decreased corneal transparency and vision.
**Clinical Pearl / High-Yield Fact**
A key clinical feature of herpes zoster keratitis is the presence of dendritic ulcers, which can be distinguished from other types of corneal ulcers by their branching, linear appearance. Early recognition and treatment of herpes zoster keratitis are essential to prevent complications and preserve vision.
**Correct Answer: D.**