In glomerulus subendothelial deposits are seen jib –
**Core Concept**
Glomerular deposits refer to the accumulation of substances within the glomerulus, which is a critical structure in the kidney responsible for filtration. Subendothelial deposits specifically refer to the presence of these substances in the space between the endothelial cells lining the glomerular capillaries.
**Why the Correct Answer is Right**
Subendothelial deposits are characteristic of membranous nephropathy, an immune-mediated disease where antibodies bind to the glomerular basement membrane (GBM), leading to its thickening. This thickening disrupts the normal filtration process, causing proteinuria. The deposits are composed of immune complexes, including IgG and complement components, which are trapped between the endothelial cells and the GBM.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because subepithelial deposits, not subendothelial deposits, are characteristic of membranous nephropathy.
**Option B:** This option is incorrect because mesangial deposits are seen in various glomerular diseases, such as IgA nephropathy, but not specifically in subendothelial deposits.
**Option C:** This option is incorrect because subcapsular deposits are seen in conditions such as tubulointerstitial nephritis, but not in subendothelial deposits.
**Clinical Pearl / High-Yield Fact**
Membranous nephropathy is a common cause of nephrotic syndrome in adults, and it often presents with massive proteinuria and hypoalbuminemia.
**Correct Answer: A. Membranous nephropathy.**