## **Core Concept**
G6PD (Glucose-6-phosphate dehydrogenase) deficiency is a genetic disorder that affects the enzyme G6PD, which protects red blood cells from oxidative damage. This deficiency makes red blood cells more susceptible to hemolysis under certain conditions, such as exposure to specific drugs, infections, or certain foods.

## **Why the Correct Answer is Right**
The correct answer, , is not a known cause of hemolysis in G6PD deficiency. Typically, hemolysis in G6PD deficiency is triggered by factors that induce oxidative stress. Common triggers include certain medications (e.g., primaquine, sulfonamides), infections, and ingestion of fava beans. does not have a well-documented association with triggering hemolysis in G6PD deficiency.

## **Why Each Wrong Option is Incorrect**
* **Option A:** is known to cause hemolysis in G6PD deficiency. It is a well-documented trigger for oxidative stress in red blood cells.
* **Option B:** can cause hemolysis in G6PD deficiency. This class of drugs is known to induce oxidative stress.
* **Option C:** is also a trigger for hemolysis. Ingestion of fava beans is a classic cause of acute hemolytic crisis in individuals with G6PD deficiency.

## **Clinical Pearl / High-Yield Fact**
A key clinical pearl is that patients with G6PD deficiency should avoid certain medications and foods known to trigger hemolysis. A classic example is avoiding fava beans (broad beans), which can cause an acute hemolytic crisis. Additionally, patients should be cautious with medications like primaquine and sulfonamides.

## **Correct Answer:** .