In development of male fetus following statements are true except

A. Gene on sho arm of Y chromosome directs tests on development

B. During intrauterine life testes has no endocrine role in fetus

C. Around 8 weeks internal and external genitalia differentiates into male pattern

D. Antimullerian hormone inhibits development of mullerian system in male fetus

Correct Answer: During intrauterine life testes has no endocrine role in fetus

Description: In males, the sex-specific gene SRY that is found on the Y-chromosome initiates sex determination by downstream regulation of sex-determining factors, (such as GATA4, SOX9, and AMH), which leads to development of the male phenotype, including directing development of the early bipotential gonad down the male path of development.Ref: Ganong&;s review of medical physiology;24th edition; page no:-425

Category: Physiology

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