In apoptosis, Apaf-1 is activated by release of which of the following substances from the mitochondria ?
Correct Answer: Cytochrome C
Description: Ans is 'd' i.e., Cytochrome CApoptosis is induced by a cascade of molecular events all of which culminate in the activation of caspases. 'In the cytosol cytochrome C binds to a protein called Apaf I (Apoptosis activating factor - 1) and the complex activates caspase 9'
Category:
Pathology
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