In anaerobic glycolysis, end product is –

Correct Answer: 2 ATP + 2 NAD
Description: Anaerobic Glycolysis ETC is not working hence NADH cannot enter ETC to form ATP. NADH is used to regenerate NAD by LDH Lactate is the end of anaerobic glycolysis. Net gain of ATP: 4 ATP produced (substrate level phosphorylation) - 2 ATP used (one by Hexokinase , other used by PFK-1) =2 ATP(net gain). 2 NAD are obtained after lactate formation but 2 NAD are used also in glyceraldehyde dehydrogenase step. So Net Gain of NAD = 0 Net gain at the end is 2ATP But here, they are asking about end product. At the end of anaerobic glycolysis, 2 ATP and 2 NAD are obtained. So when asked about end product then you have to mark 2ATP + 2NAD. But if asked about net gain then mark only 2 ATP.
Category: Biochemistry
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