In an inflamatory response, which of the following are involved in the recognition of the microbes or damaged cells?
Correct Answer: All of the above
Description: Pattern recognition receptors are located in all the cellular compartments where pathogens may be present: plasma membrane receptors detect extracellular pathogens, endosomal receptors detect ingested microbes, and cytosolic receptors detect microbes in the cytoplasm.
Several classes of these receptors have been identified:
Toll-Like Receptors
NOD-Like Receptors and the Inflammasome
Other Receptors for Microbial Products: C-type lectin receptors (CLRs), RIG- like receptors, Mannose receptors.
Reference-Robbins BASIC PATHOLOGY 10th edition pg-122,123
Category:
Pathology
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