In aluminum phosphide poisoning not true is –
**Question:** In aluminum phosphide poisoning not true is -
A. Treatment involves administering activated charcoal
B. The poisoning is not associated with gastrointestinal manifestations
C. Management focuses on supportive care only
D. The poisoning is not associated with acute renal failure
**Core Concept:**
Aluminum phosphide is a highly toxic substance, commonly used as a fumigant for grain storage. Following ingestion, aluminum phosphide produces phosphine gas, which causes severe systemic toxicity, including gastrointestinal, hepatic, and renal involvement.
**Why the Correct Answer is Right:**
Correct answer C (management focuses on supportive care only) is incorrect due to the severe nature of aluminum phosphide poisoning. Treatment options should not be limited to supportive care only. Active interventions like gastric lavage, administration of activated charcoal, and hemodialysis are essential to counteract phosphine toxicity.
**Why Each Wrong Option is Incorrect:**
A. Administration of activated charcoal helps in adsorbing phosphine gas, reducing its systemic absorption and subsequent toxicity.
B. Gastrointestinal manifestations are common in aluminum phosphide poisoning due to phosphine gas-induced inflammation, ulceration, and perforation of the gastrointestinal tract.
D. Acute renal failure is a significant complication of aluminum phosphide poisoning, resulting from phosphine gas-induced tubular necrosis and other renal injuries.
**Clinical Pearl / High-Yield Fact:**
In aluminum phosphide poisoning, active management is essential to mitigate the severe complications caused by phosphine gas. Timely intervention with gastric lavage, activated charcoal, and dialysis can significantly improve patient outcomes.