In alcohol withdrawal, drug of choice is: REPEAT
**Core Concept**
Alcohol withdrawal syndrome is a condition that occurs when an individual who has been consuming alcohol heavily for a prolonged period suddenly stops or significantly reduces their alcohol intake. The underlying principle being tested is the management of alcohol withdrawal syndrome using pharmacological interventions. **Benzodiazepines** are commonly used in this context.
**Why the Correct Answer is Right**
The correct answer is likely a benzodiazepine, as these drugs are effective in managing the symptoms of alcohol withdrawal, such as anxiety, tremors, and seizures. **Diazepam** is a specific benzodiazepine that is often used due to its long half-life and ability to cross the blood-brain barrier quickly. It acts on the **GABA receptor** to enhance the inhibitory effects of **GABA**, thereby reducing the excitability of neurons.
**Why Each Wrong Option is Incorrect**
**Option A:** Other drugs may not have the same efficacy in managing alcohol withdrawal symptoms.
**Option B:** While other benzodiazepines could be used, the question asks for the drug of choice.
**Option D:** Non-benzodiazepine options are not typically the first line of treatment for alcohol withdrawal.
**Clinical Pearl / High-Yield Fact**
It is essential to remember that **benzodiazepines** should be tapered off gradually to prevent rebound withdrawal symptoms.
**Correct Answer:** D. Diazepam.