In acute myeloid leukemia, Auer rods are numerous in: September 2009
Correct Answer: M3
Description: Ans. B: M3 The diagnosis of AML is based on the presence of at least 20% myeloid blasts in the bone marrow. Myeloblast have delicate nuclear chromatin, two to four nucleoli, and more voluminous cytoplasm than lymphoblasts. The cytoplasm often contains fine, peroxidase-positive azurophilic granules. Auer rods, distinctive needle like azurophilic granules, are present in many cases; they are paicularly numerous in AML with the t(15;17) (acute promyelocytic leukaemia-M3).
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Pathology
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