In a child admitted with H. Influenza meningitis, Cefotaxime was staed instead of ampicillin. Which of these is the likely reason for this?
Correct Answer: H. influenzae stains known to produce Beta lactamase
Description: Ans. (a) H. influenzae stains known to produce Beta lactamase Approximately 20-35% of nontypable strains of hemophilus produce 13-lactamase. In addition to 0-lactamase alteration of penicillin binding proteins is a second mechanism of ampicillin resistance has been detected in isolates of H. influenzae.
Category:
Microbiology
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