In a case of vesicular mole, all of following are high risk factors for the development of choriocarcinoma, EXCEPT:

Correct Answer: Uterus size larger than 16 week
Description: High risk factors which indicates the development of choriocarcinoma at the time of diagnosis of a hydatidiform mole are: Maternal age more than 40 years Excessive uterine enlargement Serum hCG levels more than 100,000mIU/ml Theca lutein cysts greater than 6 cm in diameter Toxemia, hypehyroidism and coagulopathy Trophoblastic embolization Previously treated choriocarcinoma Ref: A Practical Approach to Gynecologic Oncology By Basu page 142.
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