Medical MCQ - In a case of Plasmodium falciparum malaria, the peripheral blood smear does not demonstrate trophozoites and schizonts. The reason for this is:

In a case of Plasmodium falciparum malaria, the peripheral blood smear does not demonstrate trophozoites and schizonts. The reason for this is:

Apoptosis of red cells because of hemozoin pigments

Lysis of red cells with malarial parasite

Infested cells are trapped in the spleen

Infested red blood cells stick to the capillaries

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Correct Answer:

Infested red blood cells stick to the capillaries

Description:

-Plasmodium falciparum is associated with infected red cells expressing PfEMP (Plasmodium falciparum erythrocyte membrane protein) leading to their attachment to the endothelial cells. -This leads to sequestration of infected red cells in the capillaries. -That's the reason for the non-appearance of trophozoites and schizonts in the peripheral blood smear.

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