**Core Concept**
The presence of immunoglobulins in breast milk is crucial for the development of the infant's immune system, providing passive immunity against infections. Among the various types of immunoglobulins, one type is predominantly found in breast milk, playing a key role in mucosal immunity.
**Why the Correct Answer is Right**
IgA is the most abundant immunoglobulin in breast milk, accounting for approximately 90% of the total immunoglobulins present. This is due to the unique properties of IgA, which enables it to provide a barrier against pathogens at mucosal surfaces, such as the gut and respiratory tract. IgA in breast milk helps to protect the infant from infections and also promotes the development of the infant's own mucosal immune system.
**Why Each Wrong Option is Incorrect**
**Option B:** IgM is the first antibody produced in response to infection and is predominantly found in serum. It is not the primary immunoglobulin present in breast milk.
**Option C:** IgG is the most abundant immunoglobulin in serum, providing long-term immunity against infections. However, it is not the primary immunoglobulin present in breast milk.
**Option D:** IgE is involved in allergic reactions and is not typically found in breast milk.
**Clinical Pearl / High-Yield Fact**
It's essential to note that the presence of IgA in breast milk is crucial for the development of the infant's immune system. Mothers with IgA deficiency may still produce other types of immunoglobulins in their breast milk, but the protective effects against infections may be compromised.
β Correct Answer: A. IgA
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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