The nurse is assigned to care for a client with cytomegalovirus retinitis and acquired immunodeficiency syndrome who is receiving foscarnet (Foscavir). The nurse carefully monitors which of the following laboratory test during the treatment with this medication, except?
## Core Concept
Foscarnet (Foscavir) is an antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS). It works by inhibiting viral DNA synthesis. Monitoring certain laboratory tests is crucial during treatment with foscarnet to prevent and manage its potential side effects.
## Why the Correct Answer is Right
Foscarnet can cause nephrotoxicity, electrolyte imbalances, and changes in renal function. Therefore, monitoring renal function and electrolyte levels is essential during treatment. The laboratory tests typically monitored include serum creatinine, blood urea nitrogen (BUN), and electrolyte levels, particularly phosphate and potassium.
## Why Each Wrong Option is Incorrect
- **Option A:** Serum creatinine - This is a critical test to monitor because foscarnet can cause nephrotoxicity, leading to increased serum creatinine levels.
- **Option B:** Blood urea nitrogen (BUN) - Like serum creatinine, BUN is a marker of renal function, and monitoring it helps in assessing the impact of foscarnet on kidney function.
- **Option D:** Phosphate levels - Foscarnet can cause electrolyte imbalances, including changes in phosphate levels, which need to be monitored.
## Why Option C is Correct (Implicitly, as it's the correct answer)
- **Option C:** Complete Blood Count (CBC) - While a CBC is a valuable test for assessing various aspects of a patient's health, including signs of infection or anemia, it is not specifically required for monitoring the direct toxic effects of foscarnet, such as nephrotoxicity or electrolyte imbalances.
## Clinical Pearl / High-Yield Fact
A key clinical pearl is that foscarnet can cause renal impairment and electrolyte disturbances. Therefore, patients on foscarnet should have their renal function and electrolytes closely monitored. This is crucial for preventing and managing adverse effects.
## Correct Answer: C. Complete Blood Count (CBC).