Pharmacology Imipenem is combined with cilastatin to: A Cilastatin prevents degradation of imipenem in kidney B Cilastatin inreases intestinal absorption of imipenem C Cilastatin inhibits beta lactamase activity D Both have synergistic activity against Pseudomonas 💡 Explanation Imipenem is combined with cilastatin to: ✓ Correct Answer: A. Cilastatin prevents degradation of imipenem in kidney