Medicine Imipenem, a newer antibiotic with a broad antibacterial spectrum, is coadministered with cilastin because – A The combination of these antibiotics is Synergistic against Pseudomonas species B Cilastin aids the gastrointestinal absorption of the active moiety, imipenem C Cilastin inhibits a Beta-lactamase that destroys imipenem D Cilastin inhibits an enzyme in the kidney that destroys imipenem 💡 Explanation Imipenem, a newer antibiotic with a broad antibacterial spectrum, is coadministered with cilastin because - ✓ Correct Answer: D. Cilastin inhibits an enzyme in the kidney that destroys imipenem