IL – I produces –
Correct Answer: T lymphocyte activation
Description: Interleukin -1
Also known as leucocyte activating factor (LAF) or B cell activating factor (BAF).
Principally secreted by macrophages and monocytes, and epithelial cells.
Other sources are B lymphocytes, fibroblasts and endothelial cells.
Immunological effects-
- Activation of T cells for the production of IL - 2.
- B cell proliferation and antibody synthesis
- Neutrophil chemotaxis and increased PMN release from bone marrow.
- Increases body temperature (important endogenous pyrogen).
- Bone marrow cell proliferation
- Induction of acute phase protein.
Category:
Microbiology
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