**Core Concept**
Gas gangrene is a severe infection caused by Clostridium perfringens, characterized by the production of alpha-toxin, which causes hypotension through the destruction of vascular endothelial cells and the release of histamine and bradykinin. The pathophysiology involves the activation of the complement system, leading to increased vascular permeability and hypotension.

**Why the Correct Answer is Right**
The correct treatment for hypotension in gas gangrene is the administration of intravenous vasopressors, specifically norepinephrine, to counteract the vasodilatory effects of alpha-toxin and maintain adequate blood pressure. Norepinephrine acts on alpha-1 and beta-1 adrenergic receptors to increase vascular tone and cardiac contractility, thereby improving blood pressure. **Option C: Norepinephrine** is the best choice for treating hypotension in this scenario.

**Why Each Wrong Option is Incorrect**
**Option A:** Administration of intravenous fluids may not be effective in treating hypotension caused by gas gangrene, as the underlying pathophysiology involves the destruction of vascular endothelial cells, leading to increased vascular permeability and fluid loss. **Option B:** Use of vasodilators, such as nitroglycerin, would exacerbate the hypotension and worsen the patient's condition. **Option D:** Administration of antibiotics alone may not be sufficient to treat the hypotension, as the primary cause is the alpha-toxin, which needs to be addressed with vasopressors.

**Clinical Pearl / High-Yield Fact**
In cases of gas gangrene, the administration of intravenous vasopressors, such as norepinephrine, is critical to maintain adequate blood pressure and perfusion of vital organs. This should be initiated promptly, in conjunction with appropriate antibiotic therapy and surgical debridement.

**Correct Answer:** C. Norepinephrine