**Core Concept**
Non-sterile hypopyon refers to the accumulation of pus or inflammatory cells in the anterior chamber of the eye, typically due to an infectious process. In ophthalmology, hypopyon is a significant finding that indicates severe inflammation or infection within the eye.

**Why the Correct Answer is Right**
Fungal infections, such as those caused by Candida or Aspergillus species, can lead to non-sterile hypopyon in the anterior chamber of the eye. This occurs due to the invasion of fungal pathogens into the cornea or uvea, triggering an intense inflammatory response and subsequent accumulation of pus. Fungal keratitis, a type of corneal infection, is a common cause of non-sterile hypopyon in fungal infections.

**Why Each Wrong Option is Incorrect**
**Option A:** Pneumococcus infection typically causes a sterile hypopyon, which is a result of a non-infectious inflammatory response to the bacterial infection, such as in acute angle-closure glaucoma or uveitis.
**Option B:** Pseudomonas infection can cause a non-sterile hypopyon, but it is more commonly associated with contact lens-related keratitis or endophthalmitis, rather than a primary fungal infection.
**Option D:** Gonococcal infection can cause a non-sterile hypopyon, but it is more commonly associated with a severe form of conjunctivitis or corneal ulcers, rather than a primary fungal infection.

**Clinical Pearl / High-Yield Fact**
Fungal infections of the eye are often associated with a history of trauma, contact lens wear, or immunocompromised states. A high index of suspicion is essential for early diagnosis and treatment of fungal keratitis or endophthalmitis.

**✓ Correct Answer: C. Fungal infection**