“Hypopyon sign” is seen in
**Core Concept**
The "hypopyon sign" refers to the accumulation of leukocytes or inflammatory cells in the anterior chamber of the eye, which can be a manifestation of various ocular and systemic conditions. This phenomenon is often associated with conditions that cause inflammation, infection, or trauma to the eye.
**Why the Correct Answer is Right**
The presence of a hypopyon sign is typically indicative of a severe inflammatory response within the eye, which can be caused by conditions such as uveitis, endophthalmitis, or trauma. In these scenarios, the inflammatory cells, including neutrophils and monocytes, migrate into the anterior chamber of the eye, leading to the characteristic accumulation of cells at the bottom of the anterior chamber. This sign is often accompanied by other symptoms such as pain, redness, and decreased vision.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because while corneal ulcers can cause inflammation, they typically do not result in the accumulation of cells in the anterior chamber, which is characteristic of a hypopyon.
**Option B:** This option is incorrect because glaucoma is a condition characterized by increased intraocular pressure, which can lead to optic nerve damage, but it is not typically associated with a hypopyon sign.
**Option C:** This option is incorrect because while retinal detachment can cause vision loss and other symptoms, it is not typically associated with a hypopyon sign.
**Clinical Pearl / High-Yield Fact**
The presence of a hypopyon sign should prompt immediate evaluation and treatment to prevent further complications, as it can be a sign of a severe and potentially vision-threatening condition.
**Correct Answer: C. Endophthalmitis**