A female has hypopigmented lesions in the centre of the forehead. Drug responsible is?
**Core Concept**
The question tests the understanding of acquired hypopigmentation due to a specific medication, which affects melanin production or distribution. This condition is a form of cutaneous side effect related to the use of certain drugs.
**Why the Correct Answer is Right**
The correct answer is related to a medication that affects the dopachrome conversion enzyme, tyrosinase, or melanocortin 1 receptor (MC1R), leading to decreased melanin production and resulting in hypopigmented lesions. This condition is often associated with the use of certain antipsychotic medications.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is likely a distractor that might relate to another condition, such as vitiligo, which is an autoimmune disease leading to hypopigmentation. However, vitiligo does not have a direct association with the use of medications.
**Option B:** This option might relate to a condition such as pityriasis versicolor, which is a fungal infection affecting the skin, causing hypopigmentation. However, it is not directly related to the use of medications.
**Option C:** This option might be a distractor that relates to a condition such as erythema multiforme, which is an autoimmune disorder affecting the skin. However, it does not cause hypopigmentation.
**Clinical Pearl / High-Yield Fact**
Acquired hypopigmentation due to medication can be a sign of an underlying systemic condition or a side effect of a medication. It is essential to consider the patient's medications, medical history, and recent changes in their treatment plan when evaluating such cases.
**Correct Answer: D. Pimozide**