Biochemistry Hyperuricemia in von Gierke disease is due to the deficiency of the following enzyme: A Defect in hypoxanthine-guanine phosphoribosyl transferase B Glucose-6-phosphatase C Xanthine oxidase D Adenosine deaminase 💡 Explanation Hyperuricemia in von Gierke disease is due to the deficiency of the following enzyme: ✓ Correct Answer: B. Glucose-6-phosphatase