Presistent hyperplastic primary vitreous may be associated with:
**Core Concept:** Presistent Hyperplastic Primary Vitreous (PHPV) is a rare congenital disorder characterized by the persistence of developmental structures that normally regress after birth, leading to retinal detachment, cataracts, and glaucoma. It is often associated with genetic syndromes, such as the Char syndrome.
**Why the Correct Answer is Right:** PHPV is typically associated with the persistent vitreous body, which is a vitreous body remnant that should regress after birth. In PHPV, the vitreous body remains and can lead to complications like retinal detachment, cataracts, and glaucoma.
**Why Each Wrong Option is Incorrect:**
A. **Option A:** Vitreous hemorrhage: This refers to the presence of blood in the vitreous body due to trauma or disease, not the persistence of the vitreous body itself.
B. **Option B:** Retinal detachment: While PHPV can contribute to retinal detachment, the correct answer focuses on the persistence of the vitreous body rather than detachment itself.
C. **Option C:** Vitreous hemorrhage: As mentioned earlier, this occurs due to trauma or disease and is not related to the persistence of the vitreous body.
D. **Option D:** Retinal detachment: This is a complication of PHPV, not the persistence of the vitreous body.
**Clinical Pearl:** PHPV is an important clinical entity for ophthalmologists to consider when examining newborns or infants, as early intervention can prevent severe vision loss.
**Correct Answer:** D. Retinal detachment
PHPV is associated with the persistence of the vitreous body, which can lead to complications like retinal detachment, cataracts, and glaucoma. While retinal detachment is a complication of PHPV, it is still related to the persistence of the vitreous body, making option D the correct answer. The other options (A, B, and C) are related to complications of PHPV but do not address the persistence of the vitreous body.