**Core Concept**
Abnormal cellular growth can lead to various changes in tissue mass, including **hyperplasia** (an increase in the number of cells) and **hypertrophy** (an increase in the size of cells). These changes are often seen in response to increased demand or stress on the tissue.
**Why the Correct Answer is Right**
Both **hyperplasia** and **hypertrophy** can occur in tissues that have the capacity for regeneration and growth, such as the liver, kidneys, and muscles. In response to increased workload or damage, these tissues can undergo **hyperplasia** to increase cell number or **hypertrophy** to increase cell size, leading to an overall increase in tissue mass.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not accurately describe a tissue that can undergo both **hyperplasia** and **hypertrophy**.
**Option B:** This option is also incorrect as it does not represent a tissue capable of both types of growth.
**Option C:** This option is incorrect because it is not a tissue that typically exhibits both **hyperplasia** and **hypertrophy**.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that **hyperplasia** and **hypertrophy** are adaptive responses to increased demand, but they can also be pathological if uncontrolled, leading to conditions such as cancer or organ dysfunction.
**Correct Answer:** D. muscle and liver tissues exhibit both phenomena.
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