**Core Concept**
Hyperparathyroidism is a condition characterized by an overproduction of parathyroid hormone (PTH) by the parathyroid glands, leading to increased calcium levels in the blood (hypercalcemia). This hormonal imbalance affects various bodily functions, resulting in a range of symptoms.

**Why the Correct Answer is Right**
The symptoms of hyperparathyroidism are diverse and multi-systemic. **Constipation and muscle weakness (Option A)** are common manifestations due to the effects of hypercalcemia on smooth muscle and neuromuscular function. **Anorexia and weight loss (Option B)** are also seen, probably due to the impact of hypercalcemia on the gastrointestinal system and overall nutritional status. **Polydipsia and polyuria (Option C)** occur as a result of the hypercalcemia-induced nephrocalcinosis and subsequent impaired renal function.

**Why Each Wrong Option is Incorrect**
**Option A:** While constipation and muscle weakness are symptoms of hyperparathyroidism, they are not the only symptoms, making this option incomplete.
**Option B:** Although anorexia and weight loss can occur in hyperparathyroidism, they are not the most characteristic or frequent symptoms.
**Option C:** Polydipsia and polyuria are indeed symptoms of hyperparathyroidism, but similar symptoms can also be seen in other conditions, such as diabetes mellitus.

**Clinical Pearl / High-Yield Fact**
It's essential to remember that the symptoms of hyperparathyroidism can be nonspecific and overlap with those of other conditions. A high index of suspicion and laboratory confirmation (e.g., elevated PTH and calcium levels) are crucial for diagnosis.

**✓ Correct Answer: D. All of the above. All of the above symptoms can be associated with hyperparathyroidism.**