**Core Concept**
The question is testing the understanding of acid-base disturbances in the context of fluid and electrolyte balance. Specifically, it is asking about the development of hyperchloremic (or hyperchloremic) acidosis, a type of metabolic acidosis characterized by an increase in chloride levels and a decrease in bicarbonate levels in the blood.
**Why the Correct Answer is Right**
Hyperchloremic acidosis typically occurs due to the administration of large amounts of chloride-rich fluids, such as normal saline, which leads to an excessive loss of bicarbonate in the kidneys. This results in a decrease in plasma bicarbonate levels, causing a metabolic acidosis. The kidneys compensate by increasing hydrogen ion excretion, but the chloride level increases as a result of the chloride-rich fluid administration. This is often seen in the context of fluid resuscitation in critically ill patients.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not relevant to the development of hyperchloremic acidosis.
**Option B:** This option may lead to a different type of acid-base disturbance, such as lactic acidosis or diabetic ketoacidosis.
**Option C:** This option may lead to a different type of electrolyte imbalance, such as hypernatremia or hyponatremia.
**Clinical Pearl / High-Yield Fact**
When administering fluids in critically ill patients, it is essential to use balanced crystalloid solutions that contain equal amounts of chloride and lactate to prevent hyperchloremic acidosis.
**Correct Answer:** C.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.