## Core Concept
Hypercalcemia refers to an elevated calcium level in the blood, which can result from various conditions affecting calcium metabolism, bone resorption, and renal function. The question requires identifying a condition not typically associated with hypercalcemia.
## Why the Correct Answer is Right
Primary hyperparathyroidism is characterized by the overproduction of parathyroid hormone (PTH), which leads to increased calcium levels in the blood by promoting bone resorption, increasing renal calcium reabsorption, and enhancing intestinal absorption indirectly through increased vitamin D activation.
## Why Each Wrong Option is Incorrect
* **Option A:** Vitamin D intoxication leads to hypercalcemia due to increased intestinal absorption of calcium and increased bone resorption.
* **Option B:** Primary hyperparathyroidism causes hypercalcemia through increased PTH levels.
* **Option D:** Multiple myeloma can cause hypercalcemia through local osteolytic lesions.
## Clinical Pearl / High-Yield Fact
A key clinical pearl is that while **familial hypocalciuric hypercalcemia (FHH)** presents with hypercalcemia, it is distinguished from primary hyperparathyroidism by its benign nature and low urinary calcium excretion. However, the question seems to be pointing towards conditions where hypercalcemia is less characteristic or not a defining feature.
## Correct Answer: .
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.