**Question:** All of the following drugs can be used in a hypertensive crisis except:-

A. Nitroglycerin
B. Nifedipine
C. Enalapril
D. Losartan

**Core Concept:** Hypertensive crisis is a severe and potentially life-threatening elevation of blood pressure that requires urgent treatment. In such cases, the goal of treatment is to lower blood pressure rapidly and safely.

**Why the Correct Answer is Right:** Nifedipine (B) is a calcium channel blocker, which is a drug class that helps lower blood pressure by dilating (widening) blood vessels. However, due to its rapid onset and short duration of action, it is not suitable for the treatment of hypertensive crises. Instead, drugs with a slower onset and longer duration of action, like Enalapril (C) and Losartan (D), are preferred to safely lower blood pressure in a hypertensive crisis.

**Why Each Wrong Option is Incorrect:**

A. Nitroglycerin (Nitroglycerin is a vasodilator, like Nifedipine, but it is not specifically indicated for hypertension treatment and can cause hypotension (low blood pressure) in severe cases, making it unsuitable for hypertensive crisis treatment.)

**Clinical Pearl:** In a hypertensive crisis, it is essential to choose medications that can rapidly lower blood pressure while minimizing the risk of hypotension. Nifedipine is not the optimal choice due to its rapid onset and short duration of action.

**Correct Answer:** C. Enalapril