On complete hydrolysis of DNA, we will get all of the following, EXCEPT:
**Question:** On complete hydrolysis of DNA, we will get all of the following, EXCEPT:
A. Nucleotides
B. Deoxyribose Nucleotide
C. Deoxyribose sugar and phosphoric acid
D. Deoxyribonucleosides
**Correct Answer:** **D. Deoxyribonucleosides**
**Core Concept:** Complete hydrolysis of DNA refers to the process of breaking down the DNA molecule into its constituent parts. DNA is a double helix structure composed of nucleotides, which are the basic building blocks. Each nucleotide is a combination of a nitrogenous base (adenine, guanine, cytosine, or thymine) and a sugar molecule (deoxyribose). Deoxyribose nucleotide is a specific type of nucleotide where the sugar molecule is deoxyribose. Deoxyribose sugar and phosphoric acid are components of the phosphodiester backbone that links the nucleotides together. Deoxyribonucleosides are single nucleosides, which are the core sugar molecules of the nucleotides.
**Why the Correct Answer is Right:** Deoxyribonucleosides are single nucleosides consisting of the sugar molecule (deoxyribose) and a nitrogenous base. Since DNA hydrolysis breaks down the nucleotides, not the nucleosides, deoxyribonucleosides are not produced during complete hydrolysis.
**Why Each Wrong Option is Incorrect:**
A. Nucleotides: These are the correct product of complete hydrolysis of DNA, as they consist of a sugar molecule (deoxyribose) and a nitrogenous base.
B. Deoxyribose Nucleotide: This is incorrect because it refers to a specific type of nucleotide where the sugar molecule is deoxyribose.
C. Deoxyribose sugar and phosphoric acid: This is incorrect because phosphoric acid is a part of the phosphodiester backbone, not the result of DNA hydrolysis.
**Clinical Pearl:** Understanding the components of DNA is essential in molecular biology, genetics, and clinical settings. The correct interpretation of DNA hydrolysis products is crucial for diagnostic and therapeutic purposes, particularly in genetic disorders and DNA sequencing techniques.