10% Dextrose Injection, USP is a sterile, nonpyrogenic solution for fluid replenishment and caloric supply in single dose containers for intravenous administration. It contains no antimicrobial agents. The flexible container is a closed system, and air is prefilled in the container to facilitate drainage. If A patient needs 7.5% dextrose 500ml. The pharmacy has 10% dextrose in stock. A. What amount of concentrate is needed? B. What amount of diluent is needed? Desired strength= 7.5% Strength in stock or available strength = 10% Desired volume = 500ml Amount of concentrate (10% dextrose) needed A= (desired strength / available strength) * (desired volume) A= (7.5% / 10%) * 500ml A= 0.75 * 500ml A= 375ml of 10% dextrose Amount of diluent= 500ml - 375ml = 125ml The preparation= 375ml of 10% dextrose + 125ml of diluent. Reference: GHAI Essential pediatrics, 8th edition