How many stop codons are seen?
Stop codons are sequences in mRNA that signal the termination of protein synthesis. There are three stop codons in the standard genetic code. Let me recall: UAA, UAG, and UGA. These are also known as amber, ochre, and opal, respectively. So the correct answer should be three.
The user's correct answer is missing the option letters and text, but the answer is likely option C or D, depending on the options given. Wait, the user's correct answer line is empty except for the letter placeholder. Since the standard answer is three, the options would probably be A. 2, B. 3, C. 4, D. 5. So the correct answer is B. 3.
Now, the wrong options: A (2) and C/D (4 or 5) are incorrect. The user might have options like A. 2, B. 3, C. 4, D. 5. So I need to explain why each is wrong. For example, option A is wrong because there are three, not two. Options C and D are incorrect because there are only three stop codons in the standard genetic code.
Clinical pearl: Remember the three stop codons as UAA (Amber), UAG (Ochre), and UGA (Opal). A mnemonic could be "A U G O A U" but maybe "UAA, UAG, UGA" is easier. Also, note that some organisms might have variations, like prokaryotes using UGA as a tryptophan codon instead, but in the standard code, there are three stop codons.
Putting it all together: The core concept is the genetic code and stop codons. The correct answer is three. The wrong options are incorrect because they don't account for all three. The clinical pearl is the three codons and the mnemonic.
**Core Concept**
Stop codons are mRNA sequences that terminate protein synthesis during translation. The standard genetic code recognizes **three stop codons**: UAA, UAG, and UGA. These do not code for amino acids and instead signal ribosomes to release the polypeptide chain.
**Why the Correct Answer is Right**
The three stop codons (UAA, UAG, UGA) are universally conserved in the genetic code. When a ribosome encounters one of these codons in the A site, release factors bind to the ribosome, hydrolyzing the bond between the polypeptide and tRNA, thereby ending translation. No aminoacyl-tRNAs recognize these codons, ensuring termination.
**Why Each Wrong Option is Incorrect**
**Option A: 2** β Incorrect. There are three, not two, stop codons in the standard genetic code.
**Option C: 4** β Incorrect. Only three codons function as stops; the fourth option reflects confusion with start codons (e.g., AUG).
**Option D: 5** β Incorrect. No eukaryotic system uses five stop codons; this is a distractor for organisms with expanded genetic codes (e.g