**Core Concept**
Genomic actions of hormones refer to the long-term effects of hormone signaling that occur through gene transcription and protein synthesis. This type of action is typically mediated by steroid hormones, thyroid hormones, and certain vitamin D metabolites, which can directly influence gene expression by binding to specific nuclear receptors.

**Why the Correct Answer is Right**
All the options listed (Thyroid hormone, 1,25 DHCC, and Cortisol) demonstrate genomic actions. Thyroid hormone, for instance, enters the nucleus and binds to thyroid hormone receptors, which then recruit coactivators and initiate transcription of target genes. Similarly, 1,25 DHCC (1,25-dihydroxycholecalciferol) binds to the vitamin D receptor (VDR), a nuclear receptor that regulates the expression of genes involved in calcium homeostasis. Cortisol, a glucocorticoid hormone, also exerts genomic effects by binding to glucocorticoid receptors, which then modulate the transcription of genes involved in glucose and lipid metabolism.

**Why Each Wrong Option is Incorrect**
**Option A:** Thyroid hormone does indeed have genomic actions, as explained above, so this option is incorrect because it is not an "all of these" type of answer.

**Option B:** 1,25 DHCC also has genomic actions, similar to cortisol, making this option incorrect for the same reason.

**Option C:** Cortisol has genomic actions, which are distinct from its rapid, non-genomic effects. Therefore, this option is incorrect because it is not an "all of these" type of answer.

**Clinical Pearl / High-Yield Fact**
It's essential to remember that the genomic actions of hormones are typically slower in onset compared to non-genomic actions, which can occur rapidly through membrane-bound receptors. Understanding the distinction between these two types of actions is crucial for appreciating the complex interplay of hormonal signaling pathways in various physiological and pathological processes.

**✓ Correct Answer: D. All of these**