## **Core Concept**
Hodgkin lymphoma (HL) is a type of lymphoma characterized by the presence of **Reed-Sternberg cells**. The treatment of Hodgkin lymphoma often involves a combination of chemotherapy, radiation therapy, or targeted therapy, depending on the stage and specific characteristics of the disease.

## **Why the Correct Answer is Right**
The correct approach to treating Hodgkin lymphoma frequently includes **ABVD chemotherapy** (Adriamycin, Bleomycin, Vinblastine, and Dacarbazine) as a first-line treatment, especially in earlier stages. This regimen has become a standard due to its efficacy and relatively favorable side effect profile compared to older regimens like **MOPP** (Mechlorethamine, Oncovin (vincristine), Procarbazine, and Prednisone), which had more long-term toxicities. **Radiation therapy** may also be used, particularly in early-stage disease, often in conjunction with chemotherapy.

## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because, although specific chemotherapy regimens are used, the option is unspecified and lacks detail.
- **Option B:** This is incorrect as it does not accurately represent a standard treatment approach for Hodgkin lymphoma.
- **Option D:** This option is incorrect as it does not specify a recognized treatment regimen for Hodgkin lymphoma.

## **Clinical Pearl / High-Yield Fact**
A key point to remember is that the introduction of **ABVD** has significantly improved the treatment outcomes for Hodgkin lymphoma, reducing the risk of long-term toxicity compared to **MOPP**. Early-stage Hodgkin lymphoma often has a high cure rate with combined modality therapy.

## **Correct Answer:** B. ABVD.