VB
Vikas Bhardwaj
Medical Technologist, AIIMS New Delhi
Updated: Apr 17, 2026
**Core Concept**
The underlying principle being tested is the understanding of **trophoblastic diseases**, which are a group of rare, abnormal pregnancies that can develop into cancer. These diseases arise from the **trophoblast cells**, which are the outer layer of cells that form the placenta.
**Why the Correct Answer is Right**
Given that the trophoblastic disease has burrowed into the **myometrium** and histopathology showed evidence of **chorionic villi**, this indicates an invasive form of trophoblastic disease that has penetrated the uterus wall. This description aligns with an **invasive mole**, a type of gestational trophoblastic disease (GTD) that invades the myometrium.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because it doesn't specify the invasive nature of the disease into the myometrium.
**Option B:** Incorrect as it refers to a non-invasive form of trophoblastic disease without myometrial invasion.
**Option C:** Incorrect because it is not a type of trophoblastic disease characterized by invasion into the myometrium with chorionic villi present.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that **invasive mole** is a type of gestational trophoblastic neoplasia (GTN) that requires prompt treatment due to its potential for local invasion and distant metastasis.
**Correct Answer:** D. Invasive Mole.