**Question:** "Biphasic pattern" on histology is seen in which tumor-

A. Ewing's sarcoma
B. Pleomorphic liposarcoma
C. Synovial sarcoma
D. Chondrosarcoma

**Core Concept:**
The term "biphasic pattern" in histopathology refers to the presence of two distinct cell types or lineages within a single tumor, which can indicate a specific type of sarcoma. Sarcomas are malignant tumors originating from connective tissue cells, including bone, cartilage, fat, muscle, and blood vessels.

**Why the Correct Answer is Right:**
The correct answer is D. Chondrosarcoma, as it is a type of sarcoma that exhibits a biphasic pattern. In chondrosarcoma, there are two components: a cartilage-forming component (hyaline cartilage or other types of cartilage) and a solid, malignant component (sarcomatous component). This pattern is not seen in the other options provided.

**Why Each Wrong Option is Incorrect:**
A. Ewing's sarcoma is a small blue round cell tumor characterized by the fusion of EWSR1 and ETS family genes, and does not exhibit a biphasic pattern.
B. Pleomorphic liposarcoma is a type of liposarcoma characterized by the presence of multiple cell types, but it does not have a biphasic pattern.
C. Synovial sarcoma is characterized by the presence of two types of cells, usually synovial cells and round cells, but not a biphasic pattern.

**Clinical Pearl:**
Understanding the biphasic pattern in sarcoma histology is crucial for accurate diagnosis and treatment planning. A correct classification helps guide prognosis and treatment options for patients. It is essential to differentiate chondrosarcoma from other tumors with a similar biphasic pattern, such as Ewing's sarcoma and synovial sarcoma, to ensure appropriate management strategies.