Hirsutism can be caused by the following except –
**Core Concept**
Hirsutism is a clinical condition characterized by excessive growth of terminal hair in women in androgen-dependent areas, such as the face, chest, and back. This condition is often associated with hyperandrogenism, which can be caused by various factors, including hormonal imbalances, genetic disorders, and certain medications.
**Why the Correct Answer is Right**
Hirsutism is typically caused by an excess of androgens, which can be produced by the ovaries, adrenal glands, or other sources. The most common causes of hirsutism include polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia, and androgen-secreting tumors. In these conditions, the increased androgen levels stimulate the growth of terminal hair in affected areas.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because while certain antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), can cause increased libido and other sexual side effects, they are not typically associated with causing hirsutism.
**Option B:** This option is incorrect because anabolic steroids, which are synthetic hormones that mimic the effects of testosterone, can cause virilization and hirsutism in women. However, the question is asking for an exception, and anabolic steroids are a known cause of hirsutism.
**Option C:** This option is incorrect because insulin resistance and hyperinsulinemia, which are common in PCOS, can lead to increased androgen production and hirsutism.
**Clinical Pearl / High-Yield Fact**
It's essential to note that hirsutism can be a symptom of an underlying endocrine disorder, and a thorough evaluation, including hormonal tests and imaging studies, is often necessary to determine the underlying cause.
**Correct Answer: A.**