Surgery Hirschsprung’s disease is due to: A Loss of ganglion cells in the sympathetic chain B Atrophy of longitudinal muscles C Failure of migration of neural crest cells from cranial to caudal direction D Malformed taenia coli 💡 Explanation Hirschsprung's disease is due to: ✓ Correct Answer: C. Failure of migration of neural crest cells from cranial to caudal direction