**Core Concept**
Hirschsprung's disease is a congenital condition characterized by the absence of ganglion cells in the distal colon, leading to functional obstruction due to the lack of peristalsis. The primary treatment aims to remove the affected segment and restore normal intestinal function.

**Why the Correct Answer is Right**
The standard surgical approach for Hirschsprung's disease involves removing the aganglionic segment, which is typically performed through a pull-through procedure. This technique involves mobilizing the normal colon up to the affected segment and then pulling it through to the anus, effectively removing the diseased portion. The procedure can be done through various techniques, including the Swenson procedure, the Soave procedure, or the Duhamel procedure. These procedures aim to maintain the blood supply to the colon and prevent complications such as necrosis.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it does not address the underlying issue of the aganglionic segment. While medications like laxatives or antispasmodics may provide temporary relief, they do not treat the underlying condition.
**Option B:** This option is incorrect as it does not involve surgical removal of the affected segment. While endoscopic procedures may be used for diagnosis, they are not sufficient for treatment.
**Option C:** This option is incorrect as it involves a procedure that is not commonly used for Hirschsprung's disease. The primary goal of treatment is to remove the affected segment, not to create a colostomy.

**Clinical Pearl / High-Yield Fact**
The "rectal biopsy" is a crucial diagnostic tool for Hirschsprung's disease, showing the absence of ganglion cells and the presence of nerve trunks in the submucosa.

**Correct Answer:** D.