Hereditary retinoblastoma develop as a result of which of the following chromosomal deletion?
Correct Answer: 13q 14
Description: Hereditary retinoblastomas develop from the deletion of Rb gene, located on chromosome 13q14. Retinoblastoma gene is a tumor suppressor gene, which serves as a break on the advancement of cells from the G1 to S phase of cell cycle.Ref: Robbins Pathologic Basis of Disease, 7th Edition, Pages 287, 289, 1372.
Category:
Pathology
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