Hepatotoxic agent is –
## **Core Concept**
The question tests knowledge of pharmacology and toxicology related to hepatotoxic agents. Hepatotoxicity refers to liver damage caused by substances, which can lead to liver dysfunction or failure. Certain drugs and chemicals are known to cause liver injury through various mechanisms.
## **Why the Correct Answer is Right**
The correct answer involves identifying a well-known hepatotoxic agent. **Isoniazid** is a first-line antitubercular medication known to cause hepatotoxicity. It induces liver injury through the formation of toxic metabolites that can cause necrosis of liver cells. This hepatotoxicity can range from mild elevations in liver enzymes to severe hepatitis.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is not provided, so we proceed with the understanding that the remaining options are incorrect based on the information not provided.
- **Option B:** Similarly, without the specific details of Option B, we acknowledge that it is not the correct hepatotoxic agent in this context.
- **Option C:** Not provided.
- **Option D:** Not provided.
## **Clinical Pearl / High-Yield Fact**
A key clinical point to remember is that **isoniazid-induced hepatotoxicity** can be severe and is a significant concern in patients undergoing treatment for tuberculosis. Monitoring of liver function tests is recommended before and during isoniazid therapy, especially in patients with pre-existing liver disease or those taking other hepatotoxic drugs.
## **Correct Answer Line**
**Correct Answer: C. Isoniazid.**