**Core Concept**
Autoimmune hepatitis (AIH) is a chronic liver disease characterized by an immune-mediated destruction of liver cells. It is a result of a complex interplay between genetic predisposition, environmental triggers, and an imbalance in the immune response.

**Why the Correct Answer is Right**
Autoimmune hepatitis typically presents with features such as elevated serum aminotransferases, hypergammaglobulinemia, and the presence of autoantibodies like ANA, SMA, and LKM-1. The liver biopsy in AIH shows a characteristic interface hepatitis with plasma cell infiltration. In contrast, a typical feature not seen in autoimmune hepatitis is the presence of a high level of serum alkaline phosphatase.

**Why Each Wrong Option is Incorrect**
**Option A:** Elevated serum aminotransferases are indeed a typical feature of autoimmune hepatitis, making this option incorrect.
**Option C:** Hypergammaglobulinemia is also a common finding in autoimmune hepatitis, so this option is incorrect.
**Option D:** The presence of autoantibodies such as ANA, SMA, and LKM-1 is a characteristic feature of autoimmune hepatitis, which makes this option incorrect.

**Clinical Pearl / High-Yield Fact**
One key differentiating feature between autoimmune hepatitis and other causes of chronic liver disease is the presence of interface hepatitis with plasma cell infiltration on liver biopsy. This histological pattern is a strong indicator of an autoimmune etiology.

**Correct Answer:** D.